Scientific Program

Day 1 :

Keynote Forum

Bernat-Carles Serdà

University of Girona, Spain

Keynote: Lecture versus self-directed methodologies in university students' learning

Time : 10:00-10:40

Biography:

Bernat-Carles Serdà is a teacher and researcher in the Health Sciences Faculty, (University of Girona, Spain). His research focuses on Quality of Life and chronic malignancies. Nowadays is supervising several theses using mixing methods in this research field. He has achieved several pre-doctoral and post-doctoral grants for international academic stays

Abstract:

This study compared the effectiveness of teaching and learning methodologies based on knowledge transfer (lecture) with approaches that emphasized self-directed learning (Problem-Based Learning [PBL] and Reflective Learning [RL]), in a sample of 230 undergraduate nursing students and 8 professors. A mixed-methods study was carried out in a university school of nursing: quantitative methods were used to analyse the outcomes achieved by university students and compared the effectiveness of the various methods based on the students final examination scores; and qualitative analysis evaluated the factors that affected student learning in each of the three study arms: lecture, PBL and RL. The quantitative results show a better score for RL compared to PBL and the traditional lecture format. Qualitative findings indicate that self-directed methodologies result in higher-quality outcomes in student acquisition of content knowledge. Our results suggest two findings: methodologies focused on knowledge transfer (lecture) and those that favour self-directed learning (PBL and RL) are complementary; each approach has specific functions that cannot be replaced by the other two; and, self-directed learning methodologies, which are distinguished by their promotion of active student participation contribute most significantly to improving student learning. (Hajrulla 2014) Various studies have recommended the promotion of these methodologies in higher education considering them a necessary pathway for the preparation of competent professionals, as our findings also suggest. (Fook 2007) In this context that self-directed learning is a key strategy to promote individual abilities for learning continuum. The PBL and RL approach can help to foster professional knowledge and quality learning in higher education. Our research contributes to better understanding of self-directed (reflective) learning and professional practice development.  We concluded that simultaneous use of diverse instructional techniques constitutes the best instructional approach. It could be useful in the future to design instruments to evaluate specific skills associated to each technique

 

Keynote Forum

Ignat Ignatov

Scientific Research Center of Medical Biophysics, Bulgaria

Keynote: Effects of electrochemically activated water catholyte and anolyte on human health

Time : 10:40-11:20

Biography:

Ignat Ignatov DSc was born on January 1, 1963 in the town of Teteven, Bulgaria. In 1976 descrebes a phenomenon in which little apertures act like optic lenses. In 1989 Ignatov majored in physics from “Kliment Ohridski” Sofia University with master degree. In 1996 he founded the Scientific and Research Center of Medical Biophysics (SRCMB) of which he is also an owner.Prof. Dr. Ignat Ignatov was a consultant of the National Center of Public Health at the Ministry of Health until 2003. The Bulgarian scientist is involved in research projects for the study of biophysical and medical effects for the influencing of human health.The Bulgarian scientist is member of Interdisciplinary thematic group, Bulgarian Academy of Sciences (BAS) for studying the properties of activated waters with head Ass. Prof. Georgi Gluhchev.From 2007 Ignat Ignatov is honorable doctor in European Academy of Natural Sciences (Germany). From 2013 he is Doctor of Science and Professor in The Russian Academy for Natural History.Prof. Ignatov is editor in chief in Bulgarian Journal of Public Health, Ministry of Health.Prof. Ignatov is Chief Editor of two US journals. The scientific directions of Prof. Dr. Ignat Ignatov DSc are – structure of water, origination of life and living matter, mountain water and longevity, high frequency color coronal discharge, nanotechnologies, astrobiology, biological effects in heavy water, entropy and time in living matter, visual analyzer, biophysical fields, biotechnologies, shungite. In 2008, together with Prof. Marin Marinov, he established an electromagnetic concept of vision. In 2010 Prof. Ignatov, together with Ass. Prof. Mosin, created a concept for the origination of life and living matter in hot mineral water.

 

Abstract:

In the process of electrochemically activation of water with electrolysis are obtained catholyte and anolyte. The device is called electrolyzer and is separated into two parts with a semi-permeable membrane. In the two sections are put two electrodes with direct current. These are cathode and anode for the waters catholyte and anolyte.

Introduction: The properties of anolyte and catholyte are measured with pH and Oxidation Reduction Potential (ORP).  The indicator pH gives information about the acidity and alkalinity of the liquids.  Oxidation Reduction Potential (ORP) is associated with electron transition processes. There is a dependence between oxidation-reduction processes and antioxidant. Results: The physical-chemical properties of the catholyte and anolyte determine their activity. The optimal values for catholyte for ORP are (-200 - -400 mV) and for pH (8.5 – 9.5). For the anolyte they are (+500 - +600 mV) and for pH (3.5 – 4.5). The following processes take place in the two sections of the electrolyzer.

In the cathode section: 2H2O + 2e- → H2 + 2OH- .

The hydrogen gas that is produced separates, and the water obtains an alkaline reactivity.The catholyte has reduction properties and there is an increase in the number of the electrons according to the control sample and negative ORP.

In the anode section: 2Н2О → 4е- + 4Н+ + О2

The separated hydrogen ions and oxygen molecules lead to an increase in the acidity of the anolyte. The anolyte has oxidation properties and there is decrease in the number of the electrons according to the control sample and positive ORP.

The values of pH and ORP of the catholyte and anolyte after certain amount of days following the water activation, change in different ways during the time.  The catholyte preserves its high alkality (pH > 8.9) for about a week, but its oxidation-reduction potential changes rapidly and becomes almost zero after the second day. On the contrary, the corresponding values of the anolyte change insignificantly (about 10%) after almost a year.The indicated properties give unique acting properties of the activated water. During the process of electrolytic decomposition particles or components are created that cannot exist outside the solution. The increased quantity of monomolecules causes changes in viscosity, diffusion, thermal and electrical conductivity, the surface tension and the catalytic activity of the catholyte and anolyte.  Water is the natural and necessary medium for most biological molecules. Changes in its composition and structure can have stimulating or inhibitory action on the processes in the living things. The increased catholyte reduction leads to increased antioxidant effects on bio molecules. Due to this reason the catholyte has protective and positive effect for oxidation stress-connected diseases such as diabetes, cancer, neurodegenerative diseases, and side effects accompanying hemodialisys. There is stimulation of immunology system.  Clinical examinations carried out by different scientists  have demonstrated positive effect in cases such as difficult healing wounds, diabetes of type 2, telomere  shortening at the cancer cells and inhibition of their growth,  suppression of side effects caused by the use of anticancer medications,  favorable influence on the blood system. Investigations have proved that the activated water was not toxic for cells and tissues, and did not have mutagenic, cancerogenic, embryotoxic or immunotoxic effects. The high oxidation of the anolyte has a strong biocidal effect on various microbes, bacteria and viruses, which leads to their retention or complete destruction. Rapid healing of wounds and inflammation, suppression of herpes and rhinitis viruses, etc. are observed. Anolyte completely eliminates Staphylococcus aureus and Escherichia coli bacteria in in vitro experiments. About the mechanism of action of catholyte and anolyteThe mechanism of influence of activated water on the living matter is not quite clear. The observed anomalous properties of this water could directly or indirectly be referred to one or other activity, but for the present a full explanation of the process is not still available.

Networking & Refreshment Break 11:20-11:40 @ Atrium Area

Keynote Forum

Bernat-Carles Serdà

University of Girona, Spain

Keynote: Defining quality of life across the cancer continuum

Time : 11:40-12:25

Biography:

Bernat-Carles Serdà is a teacher and researcher in the Health Sciences Faculty, (University of Girona, Spain). His research focuses on Quality of Life and chronic malignancies. Nowadays is supervising several thesis using mixing methods in this research field. He has achieved several predoctoral and post-doctoral grants for international academic stays

Abstract:

Introduction: The QoL paradigm is multidimensional, dynamic and modular, and its definition differs across the cancer continuum. The challenge in the interpretation of QoL data in clinical research is that QoL is influenced by psychological phenomena such as adaptation to illness.
Purpose: This research aims to obtain a valid and sensitive assessment of QoL change over the cancer continuum, and to evaluate a rehabilitation programme aimed at inverting the observed decrease in QoL when patients return to daily living activities.
Design: The sample comprised 66 men. Patients were first assessed to establish a baseline (P1-diagnosis). This was followed by a posttest (P2-discharge) and a then-test measurement (P3-retrospective evaluation) and after returning home patients were randomized in experimental and control groups. The experimental group attended a rehabilitation programme over 24 weeks (P4).
Results: The results show that from baseline to post-test, QoL decreased significantly. The recalibration then-test confirmed a low QoL in all periods evaluated. Significant differences between the experimental and control groups proves the positive effect of the Exercise Rehabilitation Programme (ERP) on QoL.
Conclusions: Understanding the real dynamic of QoL over time would help to adapt rehabilitation programmes by improving sensitivity and efficacy and provide professionals with a more accurate perception of the impact of treatment and side effects on patients’ QoL. Our results underline the importance of changing the approach adopted by health professionals towards one of proactive management on patients’ QoL until their complete recovery in daily life.
 

  • Forensic Nursing | Nursing|Immune Response | Cardiovascular Nursing | Public Health Nursing | Oncology Nursing | Neonatology Nutrition

Session Introduction

Lucy Love

Mountain Healthcare, UK

Title: Developing the nurse role in paediatric forensic examinations across the UK
Speaker
Biography:

Lucy Love is an Associate Medical Director for Mountain Healthcare, a major provider of forensic medical services and SARCs (Sexual Assault Referral Centers) for complainants of sexual assault in the UK.  She has been a Sexual Offences Examiner for 20 years, including the evaluation of child sexual abuse and regularly appears in court as an expert witness. She is a recognized trainer of Sexual Assault Nurse Examiners and Pediatric Medical Examiners in the UK. She also works in the NHS as a Psychosexual Therapist.
 

Abstract:

The role of the nurse as a Pediatric Sexual Assault  Examiner [SANE] has been established in the USA for many years. However, in the UK, this role has traditionally been carried out by doctors (Pediatricians and Forensic Medical Examiners -FMEs). Pediatrician’s are a limited resource, already overloaded with their general pediatric work  and often unwilling to work in the highprofile arena of Child Sexual Abuse [CSA]. Forensic nurses are already used widely and successfully across the UK to examine adult complainants of rape. The training requirements to enable  nurses to provide a reliable, high quality pediatric forensic service  are discussed for areas of the UK, where pediatricians are unable or unwilling to perform the role.
 

Break: Lunch Break: 13:00-14:10 @ Orchard Restaurants

Steven Osterhout DC

Vitality Healthcare, USA

Title: Identifying environmental and lifestyle antagonists that stifl e short-term healthy immune behavior while eventually reducing appropriate long-term immune function

Time : 14:05-14:35

Speaker
Biography:

Steven Osterhout DC, CCN is the founder and director of Vitality Healthcare, an integrative medical and natural healing centre catering to identifying the underlying causes of poor health with remarkable positive patient outcomes.  He attained is Pre-Med from Western Michigan University, going on to earn his Doctorate from Palmer, as well as a postdoctoral Board Certification in Clinical Nutrition.  He is a member of the Academy of Anti-Aging Medicine, Academy of Environmental Medicine, and the Institute for Functional Medicine.  He is the published author of The Diabetic Doctor and has over twenty years of experience traveling the world investigating the most favourable approaches to accelerate the healing process

Abstract:

Multiple inflammatory mechanisms are activated by today’s lifestyle choices and environmental exposures. Common consequences include reduced immune function as well as loss of immune tolerance. Environmental exposures to common chemicals like bisphenol A, parabens, phthalates and other toxicants drive endocrine disruption. These estrogen mimicking compounds support a physiology of estrogen dominance and contribute to molecular mimicry. Constant daily exposure not only stifles immune function it also opens the door to inflammatory dysregulation and autoimmune behaviour. Increased inflammatory responses combined with perpetual feedback inflammatory cycles creates short term acute symptoms while manifesting under-recognized associated chronic degenerative disease expression. These inflammatory daily exposures provide an underlying contribution to gastrointestinal dysfunction called hyper-permeable bowel and neurological permeability. While governmental chemical regulation is sluggish in response to these common toxicants, modifying personal exposure and limiting bioaccumulation will decrease potential of autoimmune activation. Observation, modification, and appropriate choices of lifestyle exposures may present a powerful tool in quieting inflammatory degenerative processes.
 

Hend M Elazazey

King Saud Binabdul Aziz University for Health sciences, KSA

Title: Effect of inspiratory muscle training on clinical outcomes of patients undergoing cardiothoracic surgeries
Speaker
Biography:

Hend M  Elazazey is Assistant Professor in Medical Surgical Nursing Department, King Saud bin-Abdulaziz University, King of Saudi Arabia, have a more than 30 years of experience in clinical and education setting both in hospital and education institutions, has more than 20 research published papers in respected international journals, supervised more than 8 master and PhD thesis, attended many national and international conferences

Abstract:

Cardiothoracic surgery is associated with a significant risk of serious complications. So, cardiothoracic surgical patients require intensive care management postoperatively. Many of these complications are likely caused in some part by the exaggerated systemic inflammatory response to Cardio-Pulmonary Bypass (CPB). Postoperative Pulmonary Complications (PPCs) are the most frequently observed complications after cardiothoracic surgery, of which pneumonia and atelectasis are the most common. PPCs have significant clinical and economic impact associated with increasing morbidity, length of stay and associated cost. Inspiratory muscle training is a therapeutic strategy that aimed at preventing postoperative pulmonary complications. This study is aimed to study the effect of inspiratory muscle training on clinical outcomes of patients underwent cardiothoracic surgeries. A quasi-experimental study was conducted in Cardiothoracic Surgery Department at Student Hospital affiliated to Tanta University. A sample of 40 adult patients of both sexes underwent cardiothoracic surgeries based on statistical power analysis were selected and divided into 2 equal groups: Group 1 (Control Group): was received routine hospital care. Group 2 (Study Group): was received pre and postoperative inspiratory muscle training which was implemented by the researcher. Three tools were used to collect data: Tool (I) Cardiothoracic Patient Assessment Tool. Tool (II) Cardiovascular and Respiratory System Assessment Tool, Tool (III) Clinical Outcome Assessment Tool. The incidence of post-operative pulmonary complications was higher in the control group (70% and 60%) while it was (30% and 25%) of the study group during the 5th and 7th post-operative day respectively. Duration of stay in ICU was longer in the control group 4-17 days while it was 2-9 days in the study group. None of the study group compared to fifth (20%) and fourth (25%) of the control group needed re-intubation and ICU readmission respectively. A high proportion of the study group (55% and 70%) had dyspnea relieved by practicing of inspiratory muscle training compared to none of the study group. Inspiratory muscle training is an effective strategy in improving patient's outcomes after cardiothoracic surgery. It was recommended that all cardiothoracic surgical patients should receive pre and post-operative inspiratory muscle training as a daily routine care.
 

Christos Drossinakis

International Academy of Scientific Healing, Germany

Title: Methods of research in vivo research of therapeutical effect in hamsters with experimental myeloid tumour of Groffi
Speaker
Biography:

Christos Drossinakis was born in 1942 in the town of Chalkida on the Greek island of Evia.After successfully completing an electrical engineering degree, Professor Drossinakis went on to specialize in experimental healing and specifically the effect of electromagnetic waves on bio systems. Over 130 university-led scientific experiments conducted to date make him the world's most credible healer.The scientific directions of  Prof. Christos Drossinakis, D.Sc. h.c. are – structure of water, high frequency color coronal discharge, biological effects in cancer cells, entropy and time in living matter, biophysical fields.Prof. Christos Drossinakis has scientific publications jointly with Prof. Ignat Ignatov, Prof. Anton Antonov, Prof. Marin Marinov, Prof. Konstantin Korotkov, Prof. Andrey Li Gendinovich, Ass. Prof. Georgi Gluhchev, Hugo Niggli, Prof. Reneta Toshkova, Ass. Prof. Oleg Mosin, etc.
 

Abstract:

The research is co-written with Prof. RenetaToshkova, Ass. Prof. Elissaveta Zvetkova и Ass. Prof. Georgi Gluhchev In over 80 institutes and centers in Europe has been proved the strong bio-influence of Drossinakis via the application of the methods biophotons (Popp), thermo vision (Schlebusch), spectrum analysis of water (Antonov, Ignatov), color coronal spectral analysis (Ignatov), gas discharge visualization (Korotkov), synchronizing of brain electromagnetic waves (Li Gendinovich) etc. Drossinakis has achieved the following results according the norm – biophoton emission (Popp) (~900 biophotons 1cm2/ 1s), (norm ~85 photones, 1cm2/1s); increasing of the temperature after bio-influence (Schlebusch) (1.6-1.8°Ð¡) (norm 0.1°Ð¡);  average energy of hydrogen bonds among water molecules according control sample (Antonov, Ignatov) (±8.2 meV) (±1.1 meV) etc. In the current study was followed the effect of influence with Infrared Thermal Field (ITF) and Electromagnetic Fields (EMF) of Christos Drossinakis over experimental myeloid tumor of  Graffi, implanted in hamsters. The study was conducted by a team under the authority of Reneta Toshkova. The working hypothesis (concept) of Drossinakis for treatment of tumors includes several facts – redistribution of the energy in the ill and healthy zones of the body, change of ion balance at molecular level and improved interchange in the cell membranes. The author’s team of Reneta Toshkova, Ignat Ignatov, Elissaveta Zvetkova and Georgi Gluhchev together with Christos Drossinakis, has conducted experimental research in model systems.The achieved results of hamsters from experimental bio-influence of Christos Drossinakis reveal their biological efficiency and can be subject of future studies. Extending the life of the hamsters is an indicator of improving immune status. The results obtained with recent data in the medical scientific literature on the positive effect of the near infrared irradiation on the structure and function of erythrocyte membrane in normal and pathological conditions. The mitochondrial polarity in cancer cells was found to be lower than that of normal cells. Drossinakis is increasing the mitochondrial polarity.
 

Tilly Pillay

University of Wolverhampton, UK

Title: Parent, family and carer education and empowerment in reducing risks for neonatal mortality: Stretching the boundaries for neonatal units
Speaker
Biography:

Tilly Pillay is a senior consultant neonatologist in the Staffordshire Shropshire and Black Country Operational Delivery Network (West Midlands, UK), honorary lecturer at the Universities of Leicester and Birmingham, and attached to the University of Wolverhampton, School of Medicine and Clinical Practice, Faculty of Science and Engineering. She has held clinical lead for her unit at the Royal Wolverhampton NHS Trust (2014-2017). Her interests are neonatal service delivery and reducing risks for neonatal mortality. She has developed and directs a parent education training package STORK and has a keen interest in parent-carer empowerment in reducing risks for mortality for current and subsequent pregnancies. She leads a national NIHR Health Service and Research Delivery Grant Opti-Prem, establishing best place of care for babies born between 27-31 weeks in England.  She also runs a consultant training course for the region, supporting networking between units, and aimed at optimising care delivered at the frontline of neonatal services in local and special care neonatal units (Supporting the Sick neonate)
 

Abstract:

As overall infant and child mortality improves globally, neonatal deaths proportionately assume a larger contribution to infant and child deaths. In working towards continued improvements in neonatal mortality rates, especially in less resource constrained environments, the role of engaging parents, family members, partners, significant others and carers (subsequently referred to as parent-carers) becomes more important. They are key partners in targeted strategies for reducing the risks associated with neonatal mortality. This concept stretches the boundaries for neonatal units, in that it proposes pro-active preventative model with parent– carer co-ownership of the concept of reducing neonatal mortality for the community.  In my talk I discuss these concepts using the example implementation and success of one such programme in the West Midlands. Here, parent-carer education, sharing information on regionally prevalent risk factors and associations with death in the first 28 days of life and in infancy, is impactful, has driven behavioural changes through acquisition of life-saving newer skills such as training on basic life support and coping with the choking child. This Participatory Learning and Action also affords parent-carers the confidence and knowledge on measures to reduce key risks in infancy such as the risk of sudden infant death, and how to recognize when their baby may be ill, facilitating timely access to appropriate health care services. Potentially these then empower parent-carers to work with health services pro-actively in measures to reduce the risks for neonatal mortality.
 

Break: Networking & Refreshment Break 16:05-16:25 @ Atrium Area

Alison Hasselder

University of East Anglia, UK

Title: How do knowledge and understanding of sleep deprivation infl uence clinical decision making of intensive care nurses when managing sleep in critically ill patients?
Speaker
Biography:

Alison Hasselder is a PhD student at Anglia Ruskin. She is currently an Adult Field Lecturer at the University of East Anglia and runs the Dissertation and Clinical Decision-Making Modules

Abstract:

Sleep deprivation holds many consequences for critically ill patients including slower recovery, decreased resistance to infection and neurological problems such as delirium (Dick-Smith 2017). A shift in nursing and institutional culture is required to apply sleep promotion strategies and research, and to minimise unpleasant outcomes for patients (Dick-Smith 2017). This paper will present provisional data from both phases of this Constructivist Grounded Theory approach. It will emphasie what has been learnt about nurses’ decision making and how this can influence the quality of sleep their patients achieve in the Intensive Care Unit (ICU).  It will particularly focus on exploring the categories, three main themes and core category of Professional and Regulatory Compliance that have now been identified as part of phase 2 of the study. The links between these will be explained. These include the theme of “not on my shift behavior” and the role that clinical audit may have on junior nurses’ decision making. Data has been collected from 15 participants that have been interviewed with semi structured, relating this to established models of decision making and cognitive processes discussed in the literature focusing on, and exploring, nurses’ decision making in relation to sleep deprivation in the ICU.
 

Break: Workshop

Mardoche Sidor

SWEET Institute, USA

Title: Training nursing staff: The secrets and soft skills
Speaker
Biography:

Sidor is a quadruple board-certified psychiatrist, with board certifications in Psychiatry and Neurology (General Adult Psychiatry), Child and Adolescent, Addiction, and Forensic, Psychiatry. He has training in public and community psychiatry, psychopharmacology and Cognitive Behavioral Therapy. He also has training in Motivational Interviewing, psychodynamic psychotherapy, play therapy, and family and couples therapy. He has clinical, teaching, and supervision experience; he has mentorship, coaching, and management, skills; and he has experience as a primary care physician, in public speaking and writing. Sidor also has skills in leadership, research, program development and project management. His overall goal is to help all health professionals, throughout the United States and globally, access the tools they need to feel empowered to provide excellent patient care while also promoting their own self-care and burnout prevention. He is the main facilitator for the SWEET Institute, and he is an Assistant Professor of Psychiatry at Columbia University. Sidor was recently the Medical Director and Chief Medical Officer for CASES (Center for Alternative Sentencing and Employment Services) where he continues to provide psychiatric care. He speaks and writes fluently in four (4) languages—French, English, Spanish, and Creole, with intermediate proficiency in Portuguese and Italian

Abstract:

Statement of the Problem: Nursing staff who are not provided with adequate training, and support on an ongoing basis are at higher risk for burnout, are less efficient and effective, and have higher rates of iatrogeny. This increases liabilities to the agency, reduces positive patient outcomes, and increases feelings of career dissatisfaction. The purpose of this workshop is to demonstrate how the use of the Socratic and Desire Methods, Collective Learning, the facilitation of Critical Thinking, and empowerment, is a powerful tool when training clinical staff.  When implemented correctly, these methods can be transferred to a variety of topics.  The SWEET Paradigm and method of training and teaching has been shown to increase feelings of empowerment, decrease feelings of burnout, increase levels of productivity and increase overall levels of career satisfaction in clinicians of varying clinical backgrounds.  In this workshop, we will explore the Why, How, and What of Training Nursing Staff.  Workshop attendees will learn how to implement the SWEET Paradigm through a parallel experience of learning the principles, techniques, steps, and do’s and don’ts of training Nursing Staff.  Role-plays will enhance the experience and attendees will also learn the secrets of developing engaging and effective curriculum content.
 

Break: Panel Discussions

Day 2 :

Keynote Forum

Olga Kubassova

Image Analysis Group, UK

Keynote: Three types of artifi cial intelligence (AI) to impact clinical research in the next 3 years

Time :

Biography:

 A mathematician with over 10 years expertise in actively managing innovation in life science companies, Olga Kubassova, PhD, is a healthcare innovator and biotech investor with passion for improving people’s health. She has co-authored over 60 publications, books and book chapters, has become a scientific adviser to the UK government and EU funding bodies. She is a founder and CEO of IAG, Image Analysis Group, the imaging clinical research organization working with top bio-pharma companies to maximize their chances of brining novel therapeutic agents to the market. She is a four-time winner of national and international "Entrepreneur of the Year" awards. Olga’s ambition is to bring truly disruptive technologies, artificial intelligence and best of machine learning to clinical practice and research, while expanding IAG's footprint and partnerships

Abstract:

Current ways of pharmaceutical Research & Development (R&D) generate poor R&D and no longer sustainable. Artificial Intelligence (AI) is already here to Increase the speed & quality of innovation in clinical R&D. The future of successful clinical R&D of novel therapeutic agents is dependent on the efficient use of smart modern technologies and data centric development approach. The use of modern technologies, such as cloud platform and wearables will allow acquire large quantities of data, often real-time and real-life; Smart ways of using data through deep learning, big data, machine learning approaches  for patient phenotyping, patient selection, trial recruitment optimization and new drug efficacy assessment will enable the life sciences industry to increase the speed and quality of innovation, while reducing costs of development. Thus, making AI and Machine Learning (ML) methodologies a major source of competitive advantage. Today is the right time for efficient collaborations between the bio-pharma industry, technology companies, academic researchers, physicians and patients. A deeper convergence between key stakeholders and advanced technologies will facilitate the discovery and development of powerful therapies, devices and advanced diagnostics to benefit patients. 

Networking & Refreshment Break 10:40-11:00 @ Atrium Area

  • Pediatric | Cardiology and Pulmonology | Nursing Practice|Nursing | Nursing Education | Immuno Oncology Healthcare | Neonatology | Immune Response

Session Introduction

Ahmadshah Farhat

University of Medical Sciences, Iran

Title: Determination of relation between mothers blood level lead with blood level of exclusively breast fed infants less than 6 months referred to Imam Reza Hospital
Speaker
Biography:

Ahmadshah Farhat assistant professor of neonatology has completed neonatology subspecialty in Mashhad University of Medical Sciences, Iran. I am vice chancellor of Neonatal Research Center in this university since 2006 and consultant neonatologist of neonatal intensive care unit since 1992 up to now.  I have published 66 papers locally and international journal, 19 books, 71 supervision of thesis in general medicine, pediatric, and neonatology, 120 participation in national and international congress with lecture and poster presentation. I was member of 50 national scientific committee during last 23 years. I have 10 scientific honors in pediatric and neonatology.
 

Abstract:

Introduction: In adults, approximately 5 to10% of ingested lead is absorbed by the digestive system. This rate is higher in children, may be as much as 40% lead which is absorbed, is distributed by blood to different organs and tissues. There is partial correlation between blood lead levels of infants and their mothers and also between Infant age and maternal job Also lead poisoning in children has been neglected in Iran. There are not designed screening programs to evaluate lead levels in children to reduce the potential toxicity of lead. In a study on children 1-7 years old in Mashhad  south east iran showed that 74/8% of children had lead levels higher than 100ug/lit. on the other hand we don’t have blood lead level of infant less than one year old, thus In this study we measured blood lead levels of mothers and her  infants under 6 months exclusively breast-fed referred to Imam Reza hospital (Mashhad-Iran) to evaluate the relation between blood lead level of breast feed infants and their mother blood lead level. 
Methods: It was a cross-sectional study of 60 mothers and their children who referred to Imam Reza Hospital Mashhad. Lead levels were determined in the laboratory of Imam Reza hospital by atomic absorption spectroscopy method. Data entered into spss16. Data analysis was done by T-Student test, chi-square and Pearson's correlation coefficient. Also KS test was used for normality of data. P value less than 0.05 considered significant.
Results: In this study the mean maternal blood lead level was 75/99 ± 31/11 µg/l . The mean level of lead in infants with exclusively breast-fed for  first 6 months was 63/6 ± 26/89µg/l  , 80% of children  were under one month and 20% between 1 and 6 months of age. 76/7% of the infants were male and 23/3% were female The mean age of children was 24/63 ± 31/81 days. Based on the data a significant  relationship between blood lead levels in infants and mothers  has been observed.(p<0/001,r=0/64) .This significant relationship also observed  to the group below one month .(p<0/001,r=0/70) But in group of more than one month, this association between mothers  and infants  lead level  was not statistically significant.( P=0/181,r=0/41) . In our study there weren’t any relationship between blood lead level in infants and child gender, economic level, place of residence, age, similar to above study
Discussion: Comparing these results with our study showed that the mean blood lead levels in mothers and infants in our study was higher than other studies.  There were direct relationship between blood lead levels in mothers and their exclusively fed breast milk infants under one month of age, but in infants between 1-6 months this relationship was not statistically significant. In our study there weren’t  any  relationship between blood lead level in infants and child gender, economic level, place of residence, age, similar to above study.
Conclusion: There were direct relationship between blood lead levels in mothers and their exclusively fed breast milk infants under one month of age, but in infants between 1-6 months this relationship was not statistically significant. Thus we advise further studies with larger sample size about effect of age of the exclusive breast
 

Faiza A Abou El-Soud Said Shahin

King Saud Bin Abdel Aziz University for Health Sciences, KSA

Title: Application of trans-theoretical model of change on foot care management among diabetic patients: Prevention better than cure
Speaker
Biography:

Faiza has completed her RN, BSN, and MSN, PhD. She was acting as assistant professor College of Nursing, Menuofiya University since 7 years before 20102017.  In addition, she was associate professor, community health nursing, RAK-MHSU, UAE for 6 years 2010-2015. Currently, she is assistant professor, community health nursing specialty, King Saud Bin Abdel Aziz University for Health Sciences - College of Nursing, Riyadh. In addition, she was chairperson of the Continues Educational development at RAK-CON-UAE and she was a member in many academic and nonacademic committees. She acts as a supervisor of postgraduate nursing students of their dissertation as well as shared in many community projects that are served community and academic fields. She had published more than ten papers in national and international journal. The area of research interest is health promotion and risk reduction at various target population in the community settings

Abstract:

Diabetic foot ulcer is one of the most common consequences of uncontrolled blood glucose level, which takes place in 15% of people with diabetes, and precedes 84% of all diabetes-related lower-leg amputations that have the adverse effect on the diabetic patients causing physical, psychosocial, and financial burden as well as an economic burden on health care system.
The aim: of the study is to improve foot care management among diabetic patients by applying the Trans theoretical Model of Change.
Design: A quasi-experimental design was conducted with a systematic random sample.
Study sample: 154 patients who were selected from the registration system were divided equally into (77 study group) and (77 control group).
Setting: the study was conducted at the outpatient diabetic clinic affiliated to Tanta University Hospital and Segar primary health care center affiliated to ministry of health, Tanat Governorate, Egypt.
Tools: three tools were used for the purpose of data collection (I) Bio-socio-demographic characteristics questionnaire ;( II) Transtheoretical Model scale and (III) Diabetes Management Self-Efficacy Scale (DMSES). A survey was conducted by using Arabic version of self-reporting questionnaire to assess the stages of change and self-efficacy among the studied groups as a baseline and during the implementation of foot care intervention program.
Results: revealed that, there was a statistical significant difference in the stages of change of the Trans theoretical Model for diabetic foot care management of the study group compared to the control group at 2, 4, and 6 months after implementation of intervention program. In addition, there was a statistical significant difference in Diabetes Management Self-Efficacy Levels between study groups who received program intervention compared to control group 6 months after intervention.
Recommendation: encouraging nurses who are dealing with diabetic patients to use the Trans theoretical Model of change or other health promotion models to enhance diabetic patient for foot care management, and adoption of healthy behavior.
Keywords: Trans-theoretical model of change, diabetic foot care management.
 

Lieselotte Eder

SRCMB, Bulgaria

Title: Physiognomical psychology and health
Speaker
Biography:

Carl Huter (1861 - 1912), researcher and independent scholar, laid the foundation for a new science, the "Physiognomical psychology". In his major work and other writings he describes his scientific research and present the resulting philosophy and ethics. The Physiognomical Psychology is the key to the discovery of individual development Potential. It is a holistic recognition method of physical, psychological, mental and spiritual systems of humans. This is the personal environment in which a person is, just as much attention paid to education as well as the influences which have a major influence. The Physiognomical Psychology is in many areas of daily life a valuable aid:health service ,strengthening of the immun system ,Education ,Partnership (friendship, marriage, family) ,Leadership ,In all questions of everyday life Those who live up to their investments, have the right job and have made the right choice of mate have the best prerequisites to be happy - a key factor in strengthening the immune system.
 

Abstract:

Carl Huter (1861 - 1912), researcher and independent scholar, laid the foundation for a new science, the "Physiognomical psychology". In his major work and other writings he describes his scientific research and present the resulting philosophy and ethics. The Physiognomical Psychology is the key to the discovery of individual development Potential. It is a holistic recognition method of physical, psychological, mental and spiritual  systems of humans. This is the personal environment in which a person is, just as much attention paid to education as well as the influences which have a major influence. The Physiognomical Psychology is in many areas of daily life a valuable aid:health service ,strengthening of the immun system, Education, Partnership (friendship, marriage, family) Leadership ,In all questions of everyday life. Those who live up to their investments, have the right job and have made the right choice of mate have the best prerequisites to be happy - a key factor in strengthening the immune system

Nagwa Salih

Alfashir university, Sudan

Title: Rheumatic heart disease in North Darfur: An alarmingly high burden and control initiative
Speaker
Biography:

Specialist in Paediatrics & Child health at Al fashir Teaching Hospital North Darfur State/ Sudan. Assistant professor of pediatrics and child heath, faculty of medicine, Al Fashir University

Abstract:

Rheumatic Heart Disease (RHD) is the most common cause of cardiac morbidity in Sudanese young people and it is particularly prevalent in Darfur area. A retrospective review of clinical and echocardiography (echo) data for children with RHD seen in Al- Fashir Hospital from 2010 to 2016 was conducted. Data from hospital statistics, outpatient, and echo clinic records were collected and analysed. A control program was started based on training modules and public awareness material (mainly training to medical assistant, nurses, and health promoter). In the study period 324 patients were admitted and 3777 patients with RHD were seen in the outpatient clinics. Complications occurred in 33% of inpatients with a case fatality of 12%. Echo revealed that 83% of patients have sever disease and 50% have a combination of more than two valves affected. Control measures focused on nurse and medical assistants’ training. Training of 50 medical assistant and nurses, 30 physicians, and 10 health promoters was achieved. Public awareness programs were conducted. We found a significant burden of RHD in Al Fashir Hospital. A control program was initiated that need substantial support from governmental and nongovernmental organization

Break: Lunch Break: 13:00-14:10 @ Orchard Restaurants

Michelle Boltz

Critical Access Hospital, USA

Title: Nurse practitioners: Providing sustainable care across diverse rural populations in the USA
Speaker
Biography:

Michelle Boltz has spent her Nursing career practicing full spectrum primary family medicine in arctic Alaska with the Inupiaq people and providing secondary hospitalist services in an isolated critical access hospital in mountainous Montana. On the forefront of rural health services, Boltz has pioneered the use of telemedicine in direct patient care and the development of sustainable organizational health care delivery systems that meet the unique needs of the diverse communities they serve

Abstract:

Health care providers in rural locations face unique logistical and resource challenges, often times as isolated professionals. Join  Boltz in an interactive sharing of individual rural nursing experiences and exploring common ground and regional ingenuity in meeting these challenges. Providing sustainable, culturally competent care requires strong integration with existing community assets and strategies that account for the distinctive circumstances of each community.  Dr. Boltz shares her experience as Chief of Village Services for the North West Arctic Alaska working together with the Alaska State Community Health Aide program providing full spectrum primary care in remote villages across the state. Rural hospital closures significantly affect both the economic and physical health of communities. Since 2010, more than 75 rural hospitals have closed with an estimated shortage of 45,000 physician providers by 2020, a crisis affecting over 90 million rural Americans. In response to this shortage, the hospitalist role is increasingly being allocated to Nurse practitioners, who have been shown to be a valuable resource by reducing length of stay and improving hospital profit compared to physician hospitalists without affecting readmissions or mortality. This shift is supported by American federal health care organizations as demonstrated by The Institute of Medicine’s landmark 2010 report, The Future of Nursing, which includes recommendations to allow Advanced  practice registered nurses (APRNs) to practice to the full extent of their education and licensure in order to increase access to and quality of care in our struggling health care system. Dr. Boltz shares her expertise in developing and implementing a successful Nurse Practitioner hospitalist program in a rural Montana critical access hospital.
 

Vipin Koushal

Post Graduate Institute of Medical Education and Research, India

Title: Level of burnout in nursing care professionals working in tertiary care centre
Speaker
Biography:

Bringing to the table a rich and diverse experience of three decades ranging from working at the grass roots as a medical officer in a primary health centre in the state of Jammu & Kashmir to being a nodal officer in the national program on organ donation in a tertiary hospital, Vipin Koushal is currently placed as Professor in the Department of Hospital Administration in Post Graduate Institute of Medical Education & Research, Chandigarh, India. In his present capacity, Koushal’s responsibilities include hospital purchase & procurement, management of private grants & poor patient cell, administration of intensive care unit and effective functionality, which enlist him as a ‘go to person’ of the teams managing any crisis in PGIMER. Leading from the front, Koushal’s contribution speaks volumes as PGIMER was awarded ‘Kayakalap Award 2015’ and later ‘Cleanest Hospital in India’ award for 2016, which were received by Koushal from worthy Prime Minister of India. Alongside, as Nodal Officer of Regional Organ & Tissue Transplant Organization under the aegis of Ministry of Health & Family Welfare, Govt. of India, he has played a pivotal role in promoting cadaver organ donation, an indicator to this effect is that PGIMER was awarded for its contribution towards the cause by Ministry of Health & Family Welfare, Govt. of India for the year 2016-17 and 2017-18 consecutively. Prior, Koushal had a four year stint as Medical Superintendent with Govt. Medical College & Hospital, Sector 32, Chandigarh where he made a mark with his robust reforms and effective hospital administration. Having many scientific papers published in national and international journals to his credit, Koushal has also contributed many chapters in various books on hospital management. An alumnus of Govt. Medical College, Jammu (J & K), Koushal obtained his master’s degree in Hospital Administration from All India Institute of Medical Sciences, New Delhi.  Presently, he lives in Chandigarh and has been very actively engaged in  reaching out the poor and needy in his local community.
 

Abstract:

Introduction: Burnout syndrome can be defined by physical and psychological emotional exhaustion, depersonalization and a low sense of personal accomplishment. Nursing Care Profession in Tertiary Care Centre has been widely acknowledged. The work carried out by these Nursing Care Professionals has been phenomenal. In Nursing Care Professionals Career burnout has turned into a common phenomenon in recent times. The basic reason is that every profession is susceptible to exhaustion and mental strain and facing psychosocial issues.

Aim and objective: This study aim is to assess the burnout in Nursing Care Professionals in Tertiary Care Centre.

Method: This study is carried out at the PGIMER, Chandigarh. The study will be a cross sectional, hospital based and the sample will be selected through purposive sampling technique. The sample will consist of 90 Nursing Care Professionals those who are working in Tertiary care centre. Sample will be selected as per the inclusion and exclusion criterion of the study. Written informed consent will be taken from the samples of either group before starting data collection. The socio-demographic sheet and Copenhagen Burnout Inventory will be applied on the selected sample.

Result & Conclusion: The results of the study will be discussed at the time of presentation

George Gomez Sacrias

London Bridge Hospital, UK

Title: Increasing the value of nursing service through leadership and mindset transformation
Speaker
Biography:

George Gomez Sacrias is presently designated as Specialist Nurse at London Bridge Hospital. Prior to that he worked as a nurse practitioner and recipient coordinator at Apollo hospitals, Chennai. He also worked as an International student coordinator during his PG period. He is a part time Motivational speaker as well.
 

Abstract:

Globally nursing as a profession is witnessing tremendous potential as a career and as a separate profession altogether. This is because of the paradigm shift in health care. Years ago, nursing was categorised as a paramedical profession, but today it’s not so. As health care grows by leaps and bounds nursing or nurses are at a very interesting position to drive health care forward. Given this evolution, my speech investigates potential problems or lack in nursing leadership today. It will address the problems such as burnout, poor retention and autonomy. My speech will deliver practical tools and resources that I have used for nursing leaders to lead the field in their respective departments. In addition to this my speech will also include and explore the use of having an efficient mindset for work and how this will be a great boon for better staff retention, job satisfaction and growth. My speech will be good balance for health care leaders and for people who would like to have an efficient mindset, which ultimately increases the value of healthcare and will make health care gen next ready

Break: Networking & Refreshment Break 15:40-16:00 @ Atrium Area

Olga Kubassova

Image Analysis Group, UK

Title: Precision i/o clinical trial: Leveraging technology to gain insight into treatment effi cacy
Speaker
Biography:

A mathematician with over 10 years expertise in actively managing innovation in life science companies, Olga Kubassova, PhD, is a healthcare innovator and biotech investor with passion for improving people’s health. She has co-authored over 60 publications, books and book chapters, has become a scientific adviser to the UK government and EU funding bodies. She is a founder and CEO of IAG, Image Analysis Group, the imaging clinical research organization working with top bio-pharma companies to maximize their chances of brining novel therapeutic agents to the market. She is a four-time winner of national and international "Entrepreneur of the Year" awards. Olga’s ambition is to bring truly disruptive technologies, artificial intelligence and best of machine learning to clinical practice and research, while expanding IAG's footprint and partnerships

Abstract:

Cancer treatment is reaching a breakthrough due to the advances in Immunotherapy. The fundamental technology behind immunotherapy is to harness the body’s own immune system to attack cancer cells. The original purpose of immune cells is to identify and destroy dangerous cells. However, cancer cells have developed the ability to hide from the immune system and therefore uncontrolled cell proliferation occurs which leads to tumour growth. In principle, immunotherapy makes cancer cells visible to the immune system. Therapies address both: they target the body’s immune cells to identify cancer cells and enable them to destroy the dangerous cells. Therefore, immunotherapies are also called targeted therapies.For the first time in cancer treatment it is possible to address tumour heterogeneity in a more specific way. Immunotherapy enables us to study and manipulate the tumour microenvironment. However, to evaluate, proof and leverage the potential of immunotherapies, it is essential to find methods which can show the changes in the tumour microenvironment non-invasively.This is where advanced medical imaging followed by computerbased analysis becomes paramount. Advanced Magnetic Resonance Imaging (MRI) in combination with algorithms to calculate quantitative imaging biomarkers offer the unique opportunity to provide sensitive and specific tumour measurements. Especially in clinical research studies which aim not only to test the safety of a drug but also the efficacy in a certain patient population, the sensitive assessment of the therapy induced tumour microenvironmental changes are crucial for bringing the drug to the market.
 

Break: Poster Presentations

Azza Awed Alguindy

King Saud Bin Abdel Aziz University for Health Sciences, KSA

Title: The patients’ lived experiences of mechanical ventilation post cardiac surgeries
Speaker
Biography:

Azza Awad Algendy is currently working as the Assistant Professor Medical Surgical & Critical Care Nursing, King Saud Bin Abdul-Aziz University for Health Sciences, Saudi Arabia. Lecturer of Critical Care & Emergency Nursing, Faculty of Nursing, Cairo University, Egypt. Have a more than 20 years of experience in clinical and education setting both in  hospitals and educational institutions. Attended many national and international conferences, workshops and seminars as presenter and speaker as well. Membership of editorial board, review committee expert panel of global illuminators research journals and conferences, Participation in King Abdul Allah International Medical Research Centre (KAIMR) in KSAU as a reviewer for research projects.
 

Abstract:

The care of mechanically ventilated patients is a fundamental component of critical care nurses' clinical practice. From the clinical experience of the investigator, it has been observed that, being connected to mechanical ventilation post cardiac surgeries was expressed as the most stressful and harsh experience to those patients. Less attention has been paid to patients' subjective experience of mechanical ventilation; even though psychological factors have been proposed as important determinants of outcomes in some patients. Therefore, the aim of this study was to explore the Patients’ lived experience of Mechanical Ventilation Post Cardiac Surgeries. Thus, this study was done in an attempt to answer the research question; what are Patients’ lived experiences of Mechanical Ventilation Post Cardiac Surgeries? Purposeful sample was used, the data saturation occurred with fourteenth participants who were willing and able to communicate their experiences. In-depth Semi-structured interview was used to collect data using a pre-prepared interview question guide which was written in the lay Arabic language in order to capture the linguistic as well as the cultural meaning of the response and to enable the participants to move freely in their descriptions.  All interviews were audio tape recorded, transcribed verbatim and analyzed using Giorgi’s methods for phenomenological analysis. Three major themes were identified through analysis of the participants' speech, these three major themes are: Intrapersonal experiences, Extra personal experiences and Interpersonal experiences. And there is obvious interrelation among those major themes its subsequent themes. Intrapersonal experiences contain two subthemes: physical experiences: breathlessness, mouth dryness, pain and physical discomfort. And emotional experiences: shock, bothering, near death, inability to endure, powerlessness, knowledge deficit, safe/unsafe. extra personal experiences include sleep disturbances, suctioning, chest physiotherapy, affected daily activities, and experience of disconnection. Interpersonal experiences include the primacy of the nurse, impaired communication, reaction toward other patients, reaction toward visiting and visitors.  Participants responses centered on spiritual aspect. Ethical principles were maintained throughout the study. The participants' identified experiences formed the basis for formulation of recommendation guidelines to improve nursing management of mechanically ventilated patient post cardiac surgeries.
 

Hamad Dailah

University of Salford, UK

Title: Nursing education program for asthmatic patients
Speaker
Biography:

Hamad is a third-year Ph.D. student in nursing education expecting graduate that will be the end of coming September 2019. He has done his Dip HE in nursing, B.S. in Nursing Science MSN in Nursing education, Salford university, 2019. He holds MSN in Nursing Education from Salford University, UK and B.S.N from the Curtin University in Australia. Recently he had designed a booklet of self-management education program for asthmatic patient, as a result, now he has over a decade of relevant work experience, including 5 years working as a staff nurse in Saudi Arabia with Mental Health Hospital and 2years working at King Fahd Central Hospital in Jizan as a Certified Nurse Assistant. At Mental Health Hospital he have had the privilege of working in the areas of patient bedside care, injury care, Alzheimer’s care, patient foot care and skin care, palliative care, and vital signs. He is proud to support the psychological, social, spiritual, and cultural needs of both residents and their families. He has Work Experience as Nursing Education Coordinator of Nursing Development and Nursing Supervisor at the Training and Scholarship Department at Jazan Health Directorate from July 4, 2012 till present. He is working as lecturer in nursing collage at Jizan University

Abstract:

Introduction: Globally, asthma is one of the major non-communicable diseases with 235 million people currently suffering from the condition. In Saudi Arabia, there is a 4% prevalence of asthma amongst the adult population. This study aimed to develop an adult asthma patient self-management education programme that took into account the Saudi context and culture.
Systematic review: A systematic review was conducted to determine the most effective way of delivering asthma self-management education programs. It was shown in the review that asthma was more prevalent in individuals with less education, with nurses had an important role in educating patients with this disease. Following analysis of this evidence alongside the Saudi context; small group education programs delivered by nurses were selected as the most appropriate means of delivering education which considered patient individual needs and cultural values to improve their health outcomes in terms of self-management.
Methods: An explanatory sequential complementary mixed methods design was adopted. This design encompassed a quasiexperiment using a pre-post-test comparative study followed by qualitative part using face-to-face interviews with patients. The intervention was an educational program developed and included topics selected based on patients’ needs in the review and following the SINA guidance. The programme was tested to determine whether it provide them with the necessary knowledge and skills to self-manage their asthma and consequently decrease their visits to emergency departments. Further, the program was also approved and co-designed with nursing staff who provide care for patients with asthma in the selected hospital and following consultation with patients. The program was delivered by nurses and other professionals who were trained to ensure the quality of delivery. Data was collected pre, post and at 3 and 6 months following the intervention and included topics related to asthma; Asthma Control Test, Asthma Self-Management Questionnaire, the Asthma Knowledge Questionnaire and the Patient Activation Measure (PAM) instrument. Prior to data collection, instruments were all translated to Arabic language, the language of participants, and validated to assure the validity of patients’ responses. Patients in the control group were able to receive the intervention after six months, the last data collection point in the study.
Findings: Analysis of the responses between the pre and post-tests demonstrate that patients with higher levels of knowledge had higher Patients’ Activation Measure scores. Patients’ scores in all data sets in phase 2 were higher than those in phase 1 which indicated the education was effective and increased confidence in self-management of their asthma. Results to date suggest that the bespoke education is relevant and provides the necessary knowledge to increase confidence and patient activation towards disease self-management and reducing complications.
Study Progress: Longer term follow-up data and qualitative interviews will be completed in late February 2019. It is anticipated that these results will confirm the educational program is suited to the Saudi Arabian context, improves knowledge and increases confidence in the self-management of asthma.
Keywords: asthma, cultural values, patients’ education, Saudi Arabia
 

Nabil Abuamer

National Disease Center, Libya

Title: Cross sectional study to determine HIV, HBV, HCV prevalence in prison population in Tripoli, Libya
Speaker
Biography:

Cross sectional study to determine HIV, HBV, HCV prevalence in prison population in Tripoli, Libya 

Abstract:

In some settings, the Human immunodeficiency virus (HIV) prevalence in prison population is 15 times higher than in the general adult population. In some countries, sexually transmitted infections, hepatitis B and C (HBV and HCV) and tuberculosis in prisons may reach up to 10 times and even 50 times as high as in the general population. The aim of this study was to determine the prevalence of HIV, HBV and HCV among prisons inmates in Tripoli, the capital city of Libya. This Cross-sectional study was conducted in the period from 1ST November 2016 to 31ST January 2017 and included four main prisons. in Tripoli. A total of 491 participants were enrolled (430 males and 61 females). The study sample was distributed as follows; 193 individuals from Albarka prison, 175 from Tajoura B prison, 62 from South Tripoli prison and 61 females from Jadayda women prison. Trained staff from the National AIDS Programme (NAP) provided counseling and testing to all the participants who voluntarily presented themselves to the study team during the investigation period. Participants were then offered blood test for HIV, HBV and HCV using rapid test. All positive results were confirmed by Elisa and western blot at the reference laboratory of the NAP. Post-test counseling was provided to all individuals with positive test results for HIV, HBV and HCV. Proper advice and referral for management and treatment was provided and ensured. Data were entered and analyzed using Epi Info 7 program. The prevalence of HIV, HBV and HCV infections among the examined prison population in Tripoli was; 2.3%, 3.1% and 2.9% respectively. The HIV figure (2.3%) in Tripoli prisons was lower than the global estimated prevalence (3%) but much higher than the prevalence among the general population in Libya (2.3% vs. 0.13%). As expected in most prison populations, HBV was higher in prisoners then that in the community (3.1% vs. 2.2%) and HCV results were.
 

Deema K Sabir

University of Westminster, UK

Title: Effects of GM-CSF, IFN-γ and IL-4 on the function of monocytes/macrophages in a model of graft versus host disease
Speaker
Biography:

Deema was awarded MSc in heamatology with distinction from the University of Westminster in 2016 and currently studies for Mphil/PhD at the same University. Princess Nourah bint Abdulrahman University, Riyadh Sasudi Arabia University of Westminster, London, UK
 

Abstract:

Acute graft versus host disease (aGVHD) is a lethal complication which limited the success of Haematopoietic Stem Cell Transplantation (HSCT). This study develops the in-vitro model of aGVHD based on using human cells and whole blood to study functional potential of human monocytes/macrophages in allogeneic reaction. It is widely accepted that monocyte differentiate into macrophages based on the differential microenvironment the growth factor granulocyte monocyte colony stimulating factor (GMCSF) and cytokine such as Interferon-gamma (IFN-γ) will polarise monocytes into classical M1 type that promotes inflammation, whereas Interleukin-4 (IL-4) will polarise monocytes towards the alternative M2 macrophages with tissue repair functions. This study proposes to generate inflammatory setting, which mimics patient’s condition after total body irradiation, then to add mismatched blood cells to trigger allogenic response similar to aGVHD.  GM-CSF and cytokines IFN-γ and IL-4 were used to allow monocytes to differentiate towards M1 or M2 macrophages.This study assessed the variation in Co-stimulatory molecules (CD80, CD86) and HLA-DR expression on the surface of responder/donor monocytes and T cells proliferation by flow cytometer. Furthermore, proinflammatory cytokines were measured by enzyme-linked immunosorbent assay (ELISA). The results show that GM-CSF, IFN-γ and IL-4 up-regulate the expression of CD86 on the surface of classical CD14+ monocytes in similar level. However, HLA-DR expression varied based on the stimulus. Unexpectedly, the effects GM-CSF and IFN-γ expression of co-stimulatory molecule CD86 on CD14+ monocytes are particularly weak comparing to the allogenic reaction untreated control. Indeed, T cell response in GVHD setting is confirmed by T cells proliferation measurements using crystal field stabilisation energy (CFSE) method, which shows the same level of response in the presence of IL-4, as that seen with the high dose of GM-CSF and IFN-γ. This implies that generally accepted views on distinct roles of M1 and M2 macrophages in inflammation need to be re-evaluated in the complex setting of aGVHD pathology.
 

Anastasia-Ervina Sela

National and Kapodistrian University of Athens, Greece

Title: Τhe effects of smoking on maternal and child health: Literature review
Speaker
Biography:

Anastasia-Ervina Sela: Postgraduate student at the National and Kapodistrian University of Athens, Specialization in Surgical Nursing, Greece 

Abstract:

Smoking before, during and after pregnancy is not an unusual behavior among the general population and can result in adverse effects on both maternal and child health. According to World Health Organization statistics in 2007, the world's largest tobacco consumption among female smokers is recorded in Greece, where 31.3% of women smoke. Surveys show that pregnant smokers are more likely to experience ectopic pregnancy, endometrial, neonatal death, precursor placenta, premature placental detachment, and premature rupture of the mast, while the odds of eliminating in the first trimester of pregnancy are 46% smokers. As reported in a related publication of the Human Reproduction Update, among about 12 million cases observed, the researchers identified nearly 174,000 malformations, which appear to be due to cigarettes. These have deformities at the extremities, rhabdomyopia, gastrointestinal, but also ocular abnormalities. An additional Dutch survey published in 2007 shows that children of smokers may have a risk of stroke or stroke as adults, while carotid stenosis is also significant. In conclusion, the best thing to do is to stop smoking before the woman attempts to conceive, otherwise if the woman smokes and pregnancy occurs, she should immediately quit smoking for a smoother pregnancy and avoid fetal birth with serious health problems.
 

Break: Awards & Closing Ceremony